Journal: Biomedicines

Article Title: Beyond Imaging and Genetic Signature in Glioblastoma: Radiogenomic Holistic Approach in Neuro-Oncology

doi: 10.3390/biomedicines10123205

Figure Lengend Snippet: Relevant radiogenomic studies predicting IDH mutational status.

Article Snippet: Zhang et al., 2016 [ ] , Machine learning algorithm to generate a model predictive of IDH genotype based on the integration of clinical features and conventional MRI features (Statistics and Machine Learning Toolbox MATLAB 2015a) , Top features resulted were age and MRI parametric intensity, texture, and shape features , 120 , AUC 0.92.

Techniques: Mutagenesis, Imaging

Journal: Biomedicines

Article Title: Beyond Imaging and Genetic Signature in Glioblastoma: Radiogenomic Holistic Approach in Neuro-Oncology

doi: 10.3390/biomedicines10123205

Figure Lengend Snippet: MRI tumor phenotype in relation to IDH mutational status and MGMT methylation status assessed by radiomic studies.

Article Snippet: Zhang et al., 2016 [ ] , Machine learning algorithm to generate a model predictive of IDH genotype based on the integration of clinical features and conventional MRI features (Statistics and Machine Learning Toolbox MATLAB 2015a) , Top features resulted were age and MRI parametric intensity, texture, and shape features , 120 , AUC 0.92.

Techniques: Methylation

Journal: Epilepsia Open

Article Title: Intrinsic brain network stability during kainic acid‐induced epileptogenesis

doi: 10.1002/epi4.70002

Figure Lengend Snippet: (A) The within‐network reliability analysis across three experimental trials (Trials 1, 2, and 3: BOLD‐fMRI scan at Days 0–1, Days 2–3, and Days 4–5, respectively) was assessed by the MN sub‐networks in the sham control group. No significant difference was observed in any sub‐networks. (B). The within‐network reliability across three trials was assessed by the MN sub‐networks in the KA group. A significantly large ICA intensity was observed in Trial 2 vs. Trial 1 in the PrR, Trial 2 vs. Trial 1 in the DHpL, and Trial 3 vs. Trial 2 in the DHpR. One asterisk (*) identifies adjusted P values lower than 0.1. (C). Intraclass correlation coefficient (ICC) reflects the test–retest reliability in four MN sub‐networks in the sham rats and KA rats. It indicated a low‐to‐excellent reliability in sham, while the average reliability dropped in the KA group.

Article Snippet: Group‐level BOLD‐fMRI data were analyzed using GICA in the Group ICA of FMRI Toolbox (GIFT) Matlab software to identify MNs during brain resting state.

Techniques: Control